1. Signaling Pathways
  2. Anti-infection
  3. HBV

HBV

HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses。 HBV causes the disease hepatitis B。 The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus。 The genus is classified as part of the Hepadnaviridae family。 HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome。 The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus。 Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination。

HBV 相关产品 (26):

Cat. No. Product Name Effect Purity
  • HY-100029
    Bay 41-4109 Inhibitor 98.92%
    BAY 41-4109是人乙型肝炎病毒 (HBV) 的有效抑制剂,IC50值为 53 nM。
  • HY-13623A
    Entecavir monohydrate Inhibitor 99.95%
    Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) 是有选择且有效地HBV抑制剂。在HepG2细胞中的EC50值为3.75 nM。
  • HY-13782
    Tenofovir Disoproxil Fumarate Inhibitor 99.80%
    Tenofovir Disoproxil Fumarate是用于治疗 HIV 和慢性乙型肝炎核苷酸逆转录酶抑制剂。
  • HY-108917
    Morphothiadin Inhibitor 99.59%
    Morphothiadin 是野生型和阿德福韦耐药 HBV 复制的有效抑制剂,其 IC50 值为 12 nM。
  • HY-112142
    AB-423 Inhibitor 99.60%
    AB-423 是一种 HBV 衣壳组装抑制剂,在细胞中,能够抑制 HBV 复制,EC50/EC90 值分别为 0.08-0.27 μM/0.33-1.32 μM。
  • HY-117650A
    RG7834 Inhibitor 99.29%
    RG7834 (RO 7020322) 是一种高度选择性、可口服的 HBV 抑制剂,在 dHepaRG 细胞中,能够有效抑制 HBV 抗原 HBsAg,HBeAg 和 HBV DNA,IC50 值分别为 2.8,2.6 和 3.2 nM。
  • HY-114314
    BA-53038B Inhibitor
    BA-53038B 是一种 HBV核心蛋白变构调节剂 (CpAM),与HAP口袋结合,以不同的方式调节HBV衣壳组装,其 EC50 值为3.32 μM。
  • HY-P1774
    Hepatitis B Virus Core 128-140
    Hepatitis B Virus Core (128-140) 是乙肝病毒核心蛋白的多肽片段。
  • HY-16468
    Squalamine Inhibitor >98.0%
    Squalamine(MSI-1256)是具有广谱抗病毒活性化的化合物。
  • HY-13986
    Merimepodib Inhibitor 98.37%
    Merimepodib是非竞争型,有口服活性的肌苷一磷酸脱氢酶 (IMPDH) 抑制剂,具有广谱抗病毒活性。
  • HY-B0255
    Adefovir dipivoxil Inhibitor 98.50%
    Adefovir Dipivoxil可阻断HBV逆转录酶。
  • HY-101954
    Inarigivir Inhibitor 99.20%
    Inarigivir (ORI-9020;SB-9000) 是一种二核苷酸,可显着减少表达乙型肝炎病毒转基因小鼠的 HBV DNA。
  • HY-112564
    JNJ-632 Inhibitor 99.36%
    JNJ-632 是一种乙型肝炎病毒 (HBV) 衣壳组装调节剂 (CAM)。
  • HY-107902
    RIG-1 modulator 1 Inhibitor 98.81%
    RIG-1 modulator 1 是一种抗病毒化合物,可以用来治疗病毒性感染包括流感病毒,HBV, HCVHIV 来自专利 WO 2015172099 A1。
  • HY-B0766
    Bicyclol Inhibitor 99.97%
    Bicyclol(SY 801)是可口服的抗HBV,HCV化合物。
  • HY-13623
    Entecavir Inhibitor 98.88%
    Entecavir(SQ 34676; BMS 200475)是有选择且有效地HBV抑制剂,在HepG2细胞中的EC50值为3.75 nM。
  • HY-B0955
    Oxethazaine Inhibitor 99.86%
    Oxethazaine是一种局部麻醉剂,在防止酸诱导的食管疼痛。
  • HY-B0017
    Telbivudine Inhibitor 99.87%
    Telbivudine是特异的HBV复制抑制剂。
  • HY-100029A
    Bay 41-4109 racemate Inhibitor 98.02%
    BAY 41-4109 racemate是BAY 41-4109的消旋体。BAY 41-4109是人乙型肝炎病毒HBV的有效抑制剂,IC50值为53 nM。
  • HY-13859
    Clevudine Inhibitor >98.0%
    Clevudine能抗乙肝病毒。
Isoform Specific Products

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