1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. MAPKAPK2 (MK2)

MAPKAPK2 (MK2)

MAP kinase-activated protein kinase 2 (MAPKAPK2) is an enzyme that in humans is encoded by the MAPKAPK2 gene. MAPKAP kinase-2 (MK2) is originally identified by its phosphorylation of glycogen synthase at serine-7 and the corresponding serine in a peptide (GS peptide-1) modelled after the N-terminus of glycogen synthase.

MAPKAP kinase-2 is a novel protein kinase activated by mitogen-activated protein kinase。 This MAP kinase activated protein kinase, termed MAPKAP kinase-2, is distinguished from S6 kinase-II (MAPKAP kinase-1) by its response to inhibitors, lack of phosphorylation of S6 peptides and amino acid sequence。

MAPKAPK2 (MK2) 相关产品 (3):

Cat. No. Product Name Effect Purity
  • HY-12834A
    MK2-IN-1 hydrochloride Inhibitor 99.19%
    MK2-IN-1 hydrochloride 是MAPKAPK2(MK2)激酶高效选择性抑制剂,IC50值0.11uM。
  • HY-12834
    MK2-IN-1 Inhibitor
    MK2-IN-1是MAPKAPK2(MK2)激酶高效选择性抑制剂,IC50值0.11uM。
  • HY-108643
    CMPD1 Inhibitor >99.0%
    CMPD1 是一种选择性且非 ATP 竞争性的 p38 MAPK 介导的 MK2 磷酸化抑制剂,表观 Ki (Kiapp) 值为 330 nM。
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